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Results for "

eosinophil chemotaxis

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17042
    Cetirizine
    2 Publications Verification

    		 Histamine Receptor Inflammation/Immunology Endocrinology
    Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
    Cetirizine
  • HY-17042A
    Cetirizine dihydrochloride
    2 Publications Verification

    P071

    		 Histamine Receptor Inflammation/Immunology Endocrinology
    Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
    Cetirizine dihydrochloride
  • HY-120629
    BMS-639623

    		CCR Inflammation/Immunology
    BMS-639623 is a potent and orally activeCCR3 antagonist with an IC50 of 0.3 nM. BMS-639623 picomolar inhibition potency against eosinophil chemotaxis (IC50=38 pM). BMS-639623 can be used for the research of asthma .
    BMS-639623
  • HY-123532
    JNJ10191584

    VUF6002

    		 Histamine Receptor Neurological Disease
    JNJ10191584 (VUF6002) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 shows 540-fold selectivity to H4 receptor over H3 receptor with a Ki value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively .
    JNJ10191584
  • HY-107558
    JNJ10191584 maleate

    VUF6002 maleate

    		 Histamine Receptor Neurological Disease
    JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H4 receptor antagonist with a Ki value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H4 receptor over the H3 receptor with a Ki value of 14.1 μM. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC50 values of 530 nM and 138 nM, respectively .
    JNJ10191584 maleate
  • HY-100660A
    Cetirizine Impurity B dihydrochloride

    		Drug Metabolite Others
    Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
    Cetirizine Impurity B dihydrochloride
  • HY-100661
    Cetirizine Impurity D

    		Histamine Receptor Inflammation/Immunology Endocrinology
    Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
    Cetirizine Impurity D
  • HY-17042AS
    Cetirizine-d4 dihydrochloride

    		Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology
    Cetirizine-d4 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
    Cetirizine-d4 dihydrochloride
  • HY-17042AS1
    Cetirizine-d8 dihydrochloride

    		Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology
    Cetirizine-d8 (dihydrochloride) is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
    Cetirizine-d8 dihydrochloride
  • HY-17042S
    Cetirizine-d4

    		Histamine Receptor Inflammation/Immunology
    Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
    Cetirizine-d4
  • HY-17042S1
    Cetirizine-d8

    		Histamine Receptor Inflammation/Immunology
    Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
    Cetirizine-d8

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